Potential Side Effects and Risks of Tegretol

Potential Side Effects and Risks of Tegretol Bipolar Disorder Treatment Medications Print Potential Side Effects and Risks of Tegretol By Marcia Purse Marcia Purse is a mental health writer and bipolar disorder advocate who brings strong research skills and personal experiences to her writing. Learn about our editorial policy Marcia Purse Medically reviewed by Medically reviewed by Daniel B. Block, MD on January 23, 2020 twitter linkedin Daniel B. Block, MD, is an award-winning, board-certified psychiatrist who operates a private practice in Pennsylvania. Learn about our Medical Review Board Daniel B. Block, MD Updated on February 04, 2020 Jose Luis Pelaez Inc / Getty Images More in Bipolar Disorder Treatment Medications Symptoms Diagnosis Tegretol, generic name carbamazepine, is an anticonvulsant that is sometimes prescribed as a mood stabilizer in bipolar disorder. In addition to seizures and bipolar disorder, its also prescribed for pain relief in trigeminal neuralgia. Most Common Tegretol Side Effects The most common side effects that occur while taking Tegretol, especially when a person initiates it, are dizziness, drowsiness, unsteadiness, nausea, and vomiting.?? Talk with your doctor if these side effects are persistent or bothersome. Also, if you experience drowsiness, its important to discuss driving with your doctor or other activities that could be dangerous if you are not fully alert. Potential for Severe Skin Rash One rare side effect of Tegretol is a serious and potentially fatal skin reaction called Stevens-Johnson syndrome and/or toxic epidermal necrolysis.?? This serious skin rash  usually occurs within the first few months of taking Tegretol. People of Asian ancestry who carry a certain gene called the HLA-B*1502 allele may be at an increased risk for developing this skin rash.?? This is why before taking Tegretol, certain patients (those with ancestry in populations where the gene may be present) will need to undergo a screening genetic blood test. That being said, an absence of the gene doesnt mean a person cannot develop a serious rash. Likewise, having the gene doesnt mean a person will absolutely develop a severe rash. This is why its critical a person on Tegretol to  follow-up frequently with their doctor for periodic skin checks. Potential for Bone Marrow Problems Another two potential rare but serious side effects of Tegretol are aplastic anemia and agranulocytosis.?? These reactions involve depression of a persons bone marrow, which is where infection-fighting cells (white blood cells), blood-making cells (red blood cells) and blood-clotting cells (platelets) are produced. Some signs of bone marrow depression to watch out include easy bruising, swollen lymph nodes, or the presence of tiny red dots (petechiae) on your bodyâ€"a sign that you are bleeding into your skin.  To monitor for bone marrow problems, your doctor will check your blood cell counts before and during treatment with Tegretol. Other Health Concerns Liver dysfunction may also occur on Tegretol?? so a blood test of your liver function will be drawn prior to starting Tegretol and at regular intervals. Signs of liver dysfunction that a person on Tegretol should watch out for include yellowing of the skin, nausea or vomiting, or a loss of appetite. Kidney problems can also occur with Tegretol. So like your liver, your urine and a kidney blood test will be checked. Heart problems, especially heart block, is another potential severe reaction??â€"its important to tell your doctor if you have ever had an abnormal electrocardiogram (ECG). Finally, eye changes may occur with Tegretol, so an eye exam is warranted before starting Tegretol and periodically when on it. Like other anticonvulsants, Tegretol may increase a persons risk of suicidal thinking and behavior. Be sure to seek emergent medical attention if you or a loved ones mood or behavior is changing and concerning while on Tegretol. What to Tell Your Doctor Be sure and tell your doctor all of your medical problems, as some may mean that you cannot take Tegretol or need to be monitored more closely while taking it. In addition, its important to provide your doctor with a list of all your medicationsâ€"this includes prescriptions, over-the-counter medications, herbals, vitamins, and any supplements. Some may interact with Tegretol and require that your Tegretol dose is decreased or increased. Its also wise to inform your doctor if you drink alcohol  and be candid about the amount and frequency. You will need to be more careful about alcohol intake while taking Tegretol and may need to cut down. Bottom Line In addition to seizures and trigeminal neuralgia, Tegretol is sometimes prescribed for people who are bipolar, either alone or in combination with other medications. While there are some risks and side effects to watch out for when taking Tegretol, the good news is that studies show this medication to be effective and generally well-tolerated in people with bipolar disorder.?? So if you are prescribed Tegretol, you are already doing the right thing by being informed. Remain an advocate for your health safety.??? Understanding Your Bipolar Treatment Plan